Dr. Joshi has 20 years of experience supporting 21 low- and middle-income countries in the technical implementation of antimicrobial resistance containment and other pharmaceutical systems strengthening activities through four U.S. Agency for International Development-funded global programs implemented by Management Sciences for Health in the United States. Before joining Management Sciences for Health, Dr. Joshi worked at Tribhuvan University's Institute of Medicine and Tribhuvan University Teaching Hospital in Nepal for nearly 20 years in various capacities, including as academic assistant dean, professor and head of clinical pharmacology, and member secretary of the Institute of Medicine Research Committee. He provided technical assistance to Nepal's Ministry of Health as a member of the Drug Advisory Committee and Nepal Medical Council. He also served as the chief editor of the Journal of Institute of Medicine and the Journal of Nepal Medical Association. Dr. Joshi has been a lead and contributing author of multiple peer-reviewed journal publications, technical leadership documents, guidebooks, and eLearning courses related to antimicrobial resistance containment, rational medicine use, pharmacovigilance, and Global Health Security Agenda. He has written, edited, and translated medicine- and health-related books. Dr. Joshi was awarded Shikchhyaa Puraskaar (an education medal) in 2002 by the Ministry of Education of Nepal.

Dr. Joshi published a book of Nepali poems, Kahaan Chha Thaaun (Where Is the Place) in 2011 and was the lyricist for a Nepali audio album by the same name released in 2012.

Dr. Joshi has a Doctor of Medicine (Pharmacology) degree from All-India Institute of Medical Sciences, New Delhi (1989), Master of Science in Clinical Pharmacology from the University of Aberdeen (1993), and Bachelor of Medicine and Bachelor of Surgery from the University of Allahabad (1983).